Another way of phrasing the question:

Lorot hi aan kaaguv kuyizaat vis mah dovah nol lok?

"Do you think an explosive projectile can fell a dragon from the sky?"

This is a more discussion-oriented question that might be a better fit in the forums. In any case, I think a missile would do in a dragon pretty good. Its scales might shield it some, but its wings would be vulnerable. It would likely not remain flying if it survived.