Animal Models for Ocular Autoimmune Diseases

The development of animal models has greatly increased our knowledge in understanding the entire mechanism of human disease development at the molecular and genetic levels. Our company is dedicated to providing animal models for ocular autoimmune diseases, including non-infectious chronic uveitis and keratoconjunctivitis. Our animal modeling services help our clients broaden their understanding of disease pathogenesis and conduct preclinical drug screening and efficacy assessments.


Non-infectious chronic uveitis and keratoconjunctivitis are two ocular autoimmune diseases designated as orphan diseases. Both diseases have an idiopathic etiology; however, the inflammatory processes during the disease are associated with immunological perturbations. The relevance of animal models of non-infectious chronic uveitis and keratoconjunctivitis depends on pathophysiological and immune components. Animal species sensitized to allergens have been used for proof-of-concept studies. In these animal models of ocular autoimmune diseases, clinical features are closely related to the specific genetic background of the model.

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Category: General